Monday, January 28, 2008

Nanostructures like Diamonds can deliver cancer drugs precisely

Nano looks like it may provide a newly precise way of aiming only at cancer cells and avoiding inflammation, thus leaving healthy cells in their natural state. Nanoengineers Mine Tiny Diamonds For Drug Delivery. Fascinating to learn that these "diamonds," which are structurally not unlike their namesake minerals, are welcomed by cells because they are so carefully organized. When cells welcome a substance, according to this report, they tend not to go haywire and express it with inflammation. Hmmm. Seems like a big useful clue in that statement for future researchers.

The technique here is to cluster several nanodiamonds together, apply the drug to the surfaces (which allows more drug to be used than with the spherical nanoparticles currently used), deliver it to the cancer site, and there let it break up--which then releases the drug.

They've even found that they can deliver nanodiamonds (without drugs) into the body and no harm comes to surrounding cells. These new guys could become the next-generation stem-cell-type magic.

Labels: , , , ,

Monday, November 05, 2007

Nano promises noninvasive cancer therapy - in Hematology/Oncology, Other Cancers

Some of the first forays into nanomedicine are looking pretty exciting. In an experiment with human liver cells, nanotubes inserted into cancer cells in vitro and heated up by radiofrequency fields have succeeded in eliminating the tumors completely. Progress in developing the therapy depends on targeting the nanotubes to hit just cancer cells within a living organism. Investigators are currently testing monoclonal antibodies, peptides, and other potential delivery vehicles for this purpose.

After decades of having no choice but to deliver treatments like chemotherapy and radiation that can't be targeted specifically at cancer cells, and having patients suffering a raft of unpleasant side effects, doctors must be pretty excited to think the day will soon come that they don't have to punish their patients with the treatment on top of what they're already suffering with the disease.

Labels: , , , , , , , ,